J.K. Simmons starrted with Tom Hanks in the Lady Killers
Hanks starred with Paul Newman in Road to Perdition
Paul Newman starred with William Holden in The Towering Inferno
How about Bette Davis

Kathleen Turner - WAR OF THE ROSES - with Michael Douglas
Michael Douglas - IT RUNS IN THE FAMILY - Kirk Douglas
Kirk Douglas - THE WAR WAGON - with John Wayne
John Wayne - THE HORSE SOLDIERS - with William Holden who was in S.O.B.
Next J.K. Simmons

George Takei was in "Star Trek" with William Shatner.
Shatner was in "Miss Congeniality" with Benjamin Bratt
Bratt was in "The River Wild" with Meryl Streep
Streep was in "The Devil Wears Prada" with Anne Hathaway
Hathaway was in "The Princess Diaries" with Julie Andrews (S.O.B)
Next up.Kathleen Turner

How about this instead?
John Candy was in Splash with Tom Hanks
Tom Hanks was in Big with Robert Loggia (S.O.B.)

This one's a long one. There might be an easier way, but this is pretty fun.
Bela Lugosi in The Black Sleep with John Carradine
John Carradine in Satans Cheerleaders with Robin Greer
Robin Greer in Angels' Brigade with Peter Lawford
Peter Lawford in Where is Parsifal? with Eric Estrada
Eric Estrada in The Cross and The Switchblade with Pat Boone
Pat Boone in State Fair with Tom Ewell
Tom Ewell in The Seven Year Itch with Robert Strauss
Robert Strauss in Stalag 17 with William Holden
Up Next. Myrna Loy
"Whenever Mrs. Kissell breaks wind, we beat the dog."

Garry Shandling was in WHAT PLANET ARE YOU FROM? with John Goodman
John Goodman - KING RALPH - w/ Peter O'Toole
Peter O'Toole - How To Steal A Million - Audrey Hepburn
Audrey Hepburn - SABRINA - with William Holden (who was in S.O.B.)
Next
Bela Lugosi

Terrence Howard in MR HOLLAND's OPUS with Richard Dreyfuss
Richard Dreyfuss in DILLINGER with Warren Oates
Warren Oates in THE WILD BUNCH with William Holden
who was in SOB
NEXT: Garry Shandling
"Someone has been tampering with Hank's memories."

Afflect was in Gigli with Pacino, Pacino was in Heat with DeNiro, Bobby D was in Jackie Brown with Samuel L. Jackson who was in Pulp Fiction with Rosanna Arquette who was in S.O.B
Next Terrence Howard

Crispin Glover was in "Teachers" with Richard Mulligan who was in S.O.B.
next one - Ben Affleck

You could have done this one quicker by going with 'Bain was in STAR! with Julie Andrews'.
He has a none speaking role (in STAR!) as one of the shop assistants at Cartier.

er - not to mention the obvious, but . . .
Gary Burghoff was in MAS*H with Loretta Swit.
Loretta Swit is in S.O.B.
I know it's late, but I was just rolling through the boards and came across this one . . .

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Sugar Geise in "Advance to the Rear"(1964) with Glenn Ford
Glenn Ford in "The Visitor"(1979) with Shelly Winters S.O.B.
O.K. Crispin Hellion Glover

Robert Ivers>G.I.BLUES, w/Elvis Presley

CHANGE OF HABIT, w/Mary Tyler Moore
SIX WEEKS, w/Dudley Moore
10, w/Julie Andrews
Julie Andrews->S.O.B.
Next up: Jordan Ladd
"Only a fool would say that." STEELY DAN

Jackie Tohn appeared on an episode of "The Sopranos" starring James Gandolfini.
James Gandolfini appeared in the 1997 Showtime remake of "12 Angry Men" with Jack Lemmon.
Jack Lemmon costarred in "That's Life" with Julie Andrews.
Julie Andrews.S.O.B.!
Next: Kristine DeBell
Emoticons are for people who haven't learned to express themselves with actual words.

Lupe Ontiveros was in "California Suite" with Walter Matthau
Walter Matthau was in "Fail Safe" with Larry Hagman
Larry HagmanS.O.B.!
Next: Jackie Tohn

Rahi Azizi was in "Deep Impact" with Robert Duvall.
Robert Duvall was in "The Godfather" with Al Pacino.
Al Pacino was in "Scarface" with Robert Loggia.
Robert LoggiaS.O.B.!
Next: Lupe Ontiveros
Emoticons are for people who haven't learned to express themselves with actual words.

Samantha Kaye was in "The Laundromat Trilogy" with Enci
Enci was in "Scott's Play" with Tom Beyer
Tom Beyer was in "Bruce Almighty" Nora Dunn
Nora Dunn was in "Bulworth" with Warren Beatty
Warren Beatty was in "Heaven Can Wait" with Hamilton Camp
Hamilton CampS.O.B.!
Next: Rahi Azizi

Kaylee Williams has an uncredited role in
The Walk In
episode of "The Beast" which starred Patrick Swayze
http://www.imdb.com/board/11363210/fullcredits#cast
Patrick Swayze was in "Red Dawn" with Harry Dean Stanton
Harry Dean Stanton was in "Kelly's Heroes" with Stuart Margolin
Stuart Margolin.S.O.B.!
Next: Samantha Kaye
Emoticons are for people who haven't learned to express themselves with actual words.

Nancy Parsons was in "Loose Cannons" with Dom DeLuise
Dom DeLuise was in "Fail Safe" with Larry Hagman
Larry HagmanS.O.B.!
Next: Kaylee Williams

Linzi Drew was in "The Rainbow Thief" starring Peter O'Toole.
Peter O'Toole starred in "Zulu Dawn" with Burt Lancaster.
Burt Lancaster starred in "Elmer Gantry" with Shirley Jones.
Shirley Jones starred in "The Music Man" with Robert Preston.
Robert PrestonS.O.B.!
Next: Nancy Parsons
Emoticons are for people who haven't learned to express themselves with actual words.

Richard Ward was in "The Jerk" with Dick O'Neill
Dick O'Neill was in "Prizzi's Honor" with Robert Loggia
Robert LoggiaS.O.B.!
Next: Linzi Drew