There already was a remake:
https://popcultmaster.com/2018/08/10/poison-girls/

"Rosamund Pike would be a great Catherine!"
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That would definitely be pretty cool to see.

Oh, Most Definitely!

Yeah she played crazy very well.

Sharon Stone really was Fantastic in the Movie.

Yeah she's hot but she is flighty.

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I would actually not be surprised at all if at some point in the future, they actually did do a Remake of the Movie.

Mmmm there is already a very similar series to BI on Hulu named Chance with a great cast.
But hey lets go with the flow and play
Nick Hugh Laurie
Catherine Margot Robbie
Beth Elizabeth Debicki
Gus Ethan Suplee or Jonnah Hill

Amber Heard as Catherine Tramell
Ryan Reynolds as Nick Curran
Dan Fogler as Gus
Rosamund Pike as Dr. Garner
Gillian Jacobs as Roxy
Thomas Ian Nicholas as Johnny Boz
Emilio Estevez as Captain Talcot
Robert Carlyle as Marty Nielsen
Helen Mirren as Hazel Dobkins
Stephen Merchant as Dr. Lamott
Jon Hamm as Dr. McElwaine
Ben Schwartz as John Correli
Kid on bike "Where you going?"
Charlie Bright "Somewhere".

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She would definitely be an interesting choice.

Katherine Heigl as Dr. Garner!

But, in my version, he'd be more than that
"Your times over, beep. We're cummin to get ya".

Hmm. Ah, yes. Money. The root of all evil.
Gus was Nick's
only
friend. And that evil bitch shish kebab'd him.

I bet he would if they paid him enough And that would put a brand new spin on his upset and Gus' murder at the end
"Your times over, beep. We're cummin to get ya".

could their be a spark between Nick and Gus, perhaps ?
Depends.
On who plays Gus.
Oh, yeah! Jack O'Connell. That would be good. Markie probably wouldn't be up for it tho.

Hmm - yes, that's what I was thinking I think the main improvement in a BI remake would be to introduce a homoerotic element to the story, could their be a spark between Nick and Gus, perhaps ?
As for Cher, yes - not the most obvious casting choice - but I think she could play the part very well ('you're the shooter?!'). And her ever changing hair could add to the mystery behind who the real killer is.
I really think however that Rachel McAdams would make an amazing Catherine. She practically played the part in Love Crime.
"Your times over, beep. We're cummin to get ya".

I wouldn't mind seeing Mark as Nick. Just think those glutes!!!!!!!!!!
Cher? Bonkers. But inspired.

Nick Curran - Mark Wharlberg
Catherine Trammell - Rachel McAdams
Roxy - Emma Stone
Beth Garner - Emily Blunt
Gus Moran - Jack O'Connell
Nilsen - John C Reilly
Hazel Dobkins - Cher
"Your times over, beep. We're cummin to get ya".

I'd hate to see it remade because so many of the younger actors today are so annoying and not as good of actors.

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Emma Watson is too skinny looking and flat chested though. At least someone like Eliza Dushku has a little more meat, or maybe I am making the meat too big of a deal?

I think Emma Watson should portray Catherine. Isn't it time she sheds her "girl-next-door" image? Wait! She did that already w/ "The Bling Ring." But, she needs to do more villainous roles!