If i see him making a joke about green slime oozing out of a character…
https://youtu.be/iPUwtyZglQI
https://youtu.be/QRTNm6GLJYI

I think it's the kind of joke that you can't help but laugh at. Men DO stare at your boobs while they are talking to you, not all men but definitely men like Peter Griffin.
It's funny, I laughed.
You stupid fuckers, you know who you are.

Ding Dong
!

Yaw? Lol I didn't remember that.
"You're a disease, and I'm the cure!" - Marion "Cobra" Cobretti

But that's what most of what Seth Macfarlane's comedy is about.
Humour is highly subjective and, hence, personal. I disagree with what you say, I actually like his jokes on their own merit without considering the intonation (of course it does help and add to the laugh).
"You're a disease, and I'm the cure!" - Marion "Cobra" Cobretti

I think that the way it was told was the funny part.
But that's what most of what Seth Macfarlane's comedy is about.
Ding Dong
!