Star fox 64 played a ton. I have every line memorized to the point I have to play the n64 version and mute the voice acting now (3ds version unfortunately removed this option).
Super mario world was the go to childhood game for a long time. I feel like I have every stitch of that game memorized and yet end with 93 instead of 96 but am unable to find what I missed and there doesn't seem to be anything missing.
Metal gear solid at least a few times.
Chrono trigger my brothers and I were obsessed with for a while. Earthbound and super mario rpg but maybe not as much.

Most of the main series Pokémon games. I played through Omega Ruby and Alpha Sapphire many times but I could say the same about Fire Red, Leaf Green, Emerald, Ruby and Sapphire.
Lars Ulrich, James Hetfield, and Kirk Hammett of Metallica ship Discord and Fluttershy

Goldeneye
As much as I played the MP, I completed the single player just as much.

MGS3. Played through it over 20+ times.

Probably Reflec Beat Colette.
Less than forget. But more than begun.

Guessing on this
Sid Meier's Alpha Centauri, Has to be over 50 "games" won, each one can take quite a while.
THPS2, if you count each sk8er separate, around 40 times.
WCW/NWO REVENGE - had to have won each belt around 30 times or so
Diablo II, with multiplayer resets and such At least 20
Chrono Trigger, if you count NG+ Probably around 18
Fallout 2, 8-12
Resident Evil II, had to be 8 to 10
Mario Kart 64, 8-10.
River City Ransom, only twice SP, probably 8 MP
Runners up Streets of Rage II(Mostly MP), SMB1(w/o warp), SMB3(No flute).
Most of these, aside from FO2, THPS2 and half the SMAC games I probably did before the year 2000. I started playing more sports games and online multiplayer after that. Really killed my re-finishing games.
Then we'll see how he does up there, without all the assistance.

Resident Action 4 by its own it's a good game but still massively overrated.
But on the RE series it's just disgraceful. It's basically a third-person shooter.
I always tell the truth, even when I lie.

Resident Action 4 is a disaster and ruined the Resident Evil series.
You know Harry I actually like RE4but at the same time I kind of agree with you. As much as I enjoy it, it is largely responsible for the series going to sh!t afterward. Every game felt like it was desperately trying to recapture or build on what RE4 did, changing the entire franchise into a completely different type of game. Would be nice if RE could go back to being a more puzzle based genuine survival horror series again (and I say that without knowing anything about RE7, and not really caring that much about it either).

Resident Action 4 is a disaster and ruined the Resident Evil series.
It does even have the wrong number in the title.
I always tell the truth, even when I lie.

I was just about to say RE4 as well. And I think I've played it on 4 different consoles too: Gamecube, PS2, Wii, and now PS4. I'd say I've probably gone through it at least 10 times, because some of the versions made you finish on normal before getting to pro, and I've done some playthroughs before using only certain weapon combinations on pro, and doing speedruns. Such a great game.
BARTYOUWANNASEEMYNEWCHAINSAWANDHOCKEYMASK?!?!

RE4 - probably about 5-6 times as well
GTA: SA - 4 or 5 times
Dark Forces II: Jedi Knight: I honestly don't even know. I played this game online for years and probably beat the single player 10 times or more.

Probably Portal, although I can't say for sure. Bioshock might be close to the top too.
You can't just have your characters announce how they feel! That makes me feel angry!

Dead Space 1.
I completed it twice on Halloween night with the lights off on my first playthrough, and have played through numerous times since.
Apparently, my son was on something called 'Acid' and was shooting a bow and arrow into a crowd.

100% Resident Evil 5 a few times
"I'm going to steal your heart on a daily basis"
Formerly known as DanteRussia

Not sure. I've never kept count. Dark Souls maybe? I've gotten 100% across all available platforms, and each 100% requires completing the game at least twice, and I know I've played through it a bunch more times (played through the game twice on my very first time). So, yeah, that's probably high on the list.
I am on fire, but an extinguisher is not required

RE2. In the end I had it down to under 2 hrs, with no saves and I was boasting about it on here yesterday, in fact. I'd often complete it twice in the same day.
I really want RE2 remastered soon!

99% Complete: [||||||||||||||||||||||||||||||||||||||||||||||||||| ]

I think it's RE4 for me. I probably ran through that thing on PS2 thirty times. I hit a point where I had all my strategies on lock.
Also the Red9 is garbage and the Mine Thrower is king.

Shadow of The Colossus. Beaten probably 70 or 80 times.

From start to finish probably Mass Effect 2 or Diablo 2.
Never trust a black man named "Chip."

Solaris.
We are friends but we'll never be as friends as before if you don't erase that votinG mess.
You need to vote me over Samael.
I always tell the truth, even when I lie.

Harry.
Let's be friends again.
Fantasy Football Champ.

Solaris
I always tell the truth, even when I lie.

This.
Fantasy Football Champ.

Resident Action 4 is a disgrace and ruined the entire Resident Evil series.
I always tell the truth, even when I lie.